Life-span effects of ionizing radiation in the beagle dog

by Roy C. Thompson

Publisher: Office of Scientific and Technical Information, U.S. Dept. of Energy, Publisher: Available from National Technical Information Service, U.S. Dept. of Commerce in [Oak Ridge, Tenn.], Springfield, VA

Written in English
Published: Pages: 323 Downloads: 852
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Subjects:

  • Ionizing radiation -- Physiological effect,
  • Beagle (Dog breed) -- Effect of radiation on,
  • Longevity,
  • Animal models in research

Edition Notes

Statementby Roy C.Thompson ; prepared for the U.S. Department of Energy, Office of Health and Environmental Research.
SeriesPNL -- 6822., PNL -- 6822.
ContributionsPacific Northwest Laboratory., United States. Dept. of Energy.
The Physical Object
Paginationix, 323 p. :
Number of Pages323
ID Numbers
Open LibraryOL17780568M

This manuscript evaluates the role of cell killing, tissue disorganization, and tissue damage on the induction of lung cancer following low dose rate radiation exposures from internally deposited radioactive materials. Beagle dogs were exposed by inhalation to 90Y, 91Y, Ce, or 90Sr in fused clay particles. Dogs lived out their life span with complete pathology conducted at the time of by: 7. iation morbidity, and tumor induction and growth. Decreased mortality from these debilitating factors results in increased average life span following exposure to minute doses of ionizing radiation. The above phenomena suggest the possibility that ionizing radiation may be essential for life. Limited data with protozoa suggest that reproduction rates decrease when they are maintained in. Females fed x 10 6 Bq/day survived to produce a second generation, but the second generation, exposed in utero and gradually raised to the treatment level by 6 months of age, had a mean life span of 3 months; observed effects in the young were pancytopenia-hemorrhagic crisis and myeloid metaplasia (bone marrow aplasia). strontium and Ra in beagle dogs. In: Life-span radiation effects studies in animals: What can they tell us? Proceedings of the twenty-second Hanford life science symposium held at Richland, Washington, September , Thompson and Mahaffey, eds., Springfield, VA, U.S. Department of Energy, pp. Caper SG, Cunningham WC ().

You can write a book review and share your experiences. Other readers will always be interested in your opinion of the books you've read. Whether you've loved the book or not, if you give your honest and detailed thoughts then people will find new books that are right for them.   The biological effects on humans of low-dose and low-dose-rate exposures to ionizing radiation have always been of major interest. The most recent concept as suggested by the International Commission on Radiological Protection (ICRP) is to extrapolate existing epidemiological data at high doses and dose rates down to low doses and low dose rates relevant to radiological protection, using Cited by: For example, it is suggested that this canopy shielded the earth from harmful ionizing (cosmic) radiation to which, in its absence, we are now all exposed. The same would have been true of the stronger magnetic field in the past, observed to be still weakening today. 1 However, the canopy is usually foremost in such explanations. EFFECTS OF LOW-DOSE-GAMMA RAYS ON THE IMMUNE SYSTEM OF DIFFERENT ANIMAL MODELS OF DISEASE Noriko Shimura Faculty of Pharmaceutical Sciences, Ohu University, Japan Shuji Kojima Faculty of Pharmaceutical Sciences, Tokyo University of Science, Japan We reviewed the beneficial or harmful effects of low-dose ionizing radiation on sever-.

Full text of "Effect of Radiation on Human Health ()" See other formats. Andersen, in , had been given an Atomic Energy [Commssion] contract, which was gotten by the dean of the veterinarian school, named George Hart, to discover the consequences on life span of [exposing] beagle dogs with a single dose of radiation or [with] fractionated doses.   Toronto, Canada – Many of us are animal lovers, and we have heard very little about the effects of the nuclear radiation on the animal kingdom in Japan and near the Fukusima Daiichi Nuclear Power Plant. The focus is centred on the residents, but what about the animals? The devastation of the earthquake, tsunami and now nuclear radiation that hit Japan on Ma has killed many and. *Wrenn ME, Taylor GN, Stevens W, et al. DOE life-span radiation effects studies in experimental animals at University of Utah, Division of Radiobiology. In: Life-span radiation effects in animals: What can they tell us? Conference: U.S. Department of Energy, *Wustrow TP, Behbehani AA, Wiebecks B.

Life-span effects of ionizing radiation in the beagle dog by Roy C. Thompson Download PDF EPUB FB2

Life-span effects - e of ionizing radiation in the beagle dog a summary account of four decades of research funded by tlie u.s. department of energy and its predecessor agenciesFile Size: 4MB.

Thompson, R. Life-span effects of ionizing radiation in the beagle dog: A summary account of four decades of research funded by the US Department of Energy and its predecessor agencies. United States: N. p., Web. doi/ Get this from a library. Life-span effects of ionizing radiation in the beagle dog: a summary account of four decades of research funded by the U.S.

Department of Energy and its predecessor agencies. [Roy C Thompson; United States. Department of Energy. Office of Health and Environmental Research.]. Life Span Effects of Ionizing Radiation in the Beagle Dog: A Summary Account of Four Decades of Research Funded by the U.S. Department of Energy and [Thompson, Roy C.] on *FREE* shipping on qualifying offers.

Life Span Effects of Ionizing Radiation in the Beagle Dog: A Summary Account of Four Decades of Research Funded by the U.S. Department of Energy andAuthor: Roy C. Thompson. From to Bill Norris and Tom Fritz performed one of several Beagle Dog Experiments at Argonne National administered external Co gamma-ray exposure at dose rates ranging from to 54 cGy/day, continued until death on 13 months old dogs of both sexes, placed on experiment in two series: "A" from toand "B" from to In addition to the Life-span effects of ionizing radiation in the beagle dog book provided below, there are several comprehensive reviews which cover the beagle dog experiments, Roy C.

Thompson's "Life-Span Effects of Ionizing Radiation in the Beagle Dog" and the "International Radiobiology Archives of Long-Term Animal Studies I. Descriptions of Participating Institutions and Studies" by Gerber. For example, Roy Thompson’s Book, Life Span Effects of Ionizing Radiation in Beagle Dogs, elucidates the most relevant findings and references from the Beagle dog experiments conducted in various national laboratories across the United States (Thompson, ).

Many more sources detail the results of individual by: Roy Thompson’s book: Life-Span Effects of Ionizing Radiation in the Beagle Dog, published inestablished the framework for combining and comparing the studies, and has become the guide to the beagle portion of the NRA database.

Bob Thomas served for many years as OHER technical monitor with responsibility for the life-span beagle studies. RSSC BIOLOGICAL EFFECTS OF IONIZING RADIATION 08/11 B. Area Exposed The portion of the body irradiated is an important exposure parameter because the larger the area exposed, other factors being equal, the greater the overall damage to the organism.

This is because more cells have been impacted and there is a greaterFile Size: KB. ELSEVIER Mechanisms of Ageing and Development 74 () Life span and cancer mortality in the Beagle dog and humans Roy E. Albert*a, Stephen A. Benjaminb, Rakesh Shuklaa aDepartment of Environmental Health, University of Cincinnati Medical Center, Eden Ave.

Cincinnati, OH, USA bCollaborative Radiological Health by: The Radioactive Beagles represented the first time that. Life-Span Effects of Ionizing Radiation in the Beagle Dog.

Life-Span Effects of Ionizing Radiation in the Beagle Dog. Prepared. 42 Rosenblatt LS, Book SA, Goldman M: Effects of x-ir-radiation of young female beagles on life-span and tumor incidence. In: Life-Span Radiation Effects Studies in An-imals: What Can They Tell Us?, ed.

Thompson RC, Me-haffey JA, pp. – Office of Scientific and Tech-nical Information, US Department of Energy, Washing-ton, DC, 1. Author(s): Thompson,Roy C; United States. Department of Energy. Office of Health and Environmental Research. Title(s): Life-span effects of ionizing radiation in the beagle dog: a summary account of four decades of research funded by the U.S.

Department of Energy and its. Immunologic and hematopoietic responses were studied in beagle dogs following prenatal or neonatal irradiation to evaluate the effects of ionizing radiation on the developing lymphohematopoietic system.

In prenatally-irradiated dogs thymic medullary volumes were significantly reduced at birth, but had returned to control levels by 12 weeks of age.

Introduction. The health effects of ionizing radiation from external sources and internally deposited radionuclides have been more extensively investigated than any other hazardous agent or class of agents (McClellan, ).Thus, ionizing radiation is an ideal toxicant to Author: Roger O.

McClellan. biological effects of ionizing radiation. This arti-cle — though by no means an account of all essential information — summarizes the high-lights of UNSCEAR's assessment of the effects of low doses of ionizing radiation, hereinafter called " low radiation doses" (see box, page 39) in the context of available radiobiological evidence File Size: KB.

The “typical” dog will survive for almost nine months after PRT, but you should be prepared for anything between three weeks, if your dog does not respond, to over 1 ½ years, if he responds exceptionally well.

Source. Palliative radiation therapy for solid tumors in dogs: cases (). Tollett MA, Duda L, Brown DC, Krick EL. Discover Book Depository's huge selection of Roy Thompson books online. Free delivery worldwide on over 20 million titles. Thompson, RC: Life-span Effects of Ionizing Radiation in the Beagle Dog.

Office of Scientific and Technical Information, US Department of Energy, Oak Ridge, TN, Google ScholarCited by: life-span effects of ionizing radiation in the beagle dog - International The idea for a report or book reviewing the total effort on life-span studies of many during the nearly 40 years that such studies have been in progress.

This. pdf. Effects of ionizing radiation on the mammalian brain Article (PDF Available) in Mutation Research/Reviews in Mutation Research December with Reads How we measure 'reads'. Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF.

Visit to get more information about this book, to buy it in print, or to download it as a free PDF. United Nations Scientific Committee on the Effects of Atomic Radiation: Ionizing Radiation Levels and Effects. Vol. 1: Levels Vol.

2: Effects Publ. IX 17, United Nations, New York. Warren, Shields, and Olive Gates, The Induction of Leuke- mia and Life Shortening in Mice by Continuous Low- Level External Gamma Radiation. For example, Roy Thompson’s Book, Life Span Effects of Ionizing Radiation in Beagle Dogs, elucidates the most relevant findings and references from the Beagle dog experiments conducted in various national laboratories across the United States (Thompson, ).

Many more sources detail the results of individual experiments. Life-span effects of ionizing radiation in the beagle dog. A summary account of four decades of research funded by the US Department of Energy and its predecessor agencies. PNL UC, US DOE Office of Health and Environmental Research under Contract DE-ACRLO 1.

Radiation Exposure quantity 2. Ability of radiation to cause ionization of tissue 3. Amount of body exposed ic body parts exposed Ionizing radiation produces the greatest amount of biologic damage in the human body when a large dose of densely ionizing (high-LET) radiation is delivered to a large or radiosensitive area of the body.

Life-span Radiation Effects Studies in Animals: What Can They Tell Us. Thompson (). Life-Span Effects of Ionizing Radiation in the Beagle Dog. National Radiobiology Archives, Richland, WA A New Book.

Or Books. The Effects on Populations of Exposure to Low Levels of Ionizing Radiation. Report of the Advisory Committee on Biological Effects of Ionizing Radiation, National Academy of Sciences-National Research Council, Wash- ington, DC9.

Grossman, J. Little and W. O'Toole. Risk of Degenerative Tissue or Other Health Effects from Radiation Exposure primary particle track (Cucinotta et al., ). The lack of epidemiological data and sparse radiobiological data on the effects of these HZE nuclei leads to a high level of uncertainty in risk estimates for long-term health effects after exposure to GCRs and Size: KB.

2 Biological Effects of Radiation rem] per year) had the potential to cause long term effects. For example, life span studies suggested that early radiologists and other radiation workers exposed to high levels of it deposits ionizing energy in the cell (Figure ).

The. Radiation workers need to be especially aware of the late effects of radiation because their exposure to radiation is usually low level over a long period of time.

Occupational radiation protection guidelines, therefore, are based on late effects of radiation according to a linear, nonthreshold dose-response curve.Real Impact of Nuclear Radiation Exposure.

NOTE: Page UNDER DEVELOPMENT. Donald Weber who extensively photographed Chernobyl and went to photograph Fukushima shortly after the 3/11/11 Nuclear Attack said "I have a feeling that people just don't really understand, they are not grasping the whole scope of the potentiality.

I think with the earthquake and tsunami, that was a catastrophe, but you.SOURCES AND EFFECTS OF IONIZING RADIATION United Nations Scientific Committee on the Effects the effects of radiation on life-span it is important to know the underlying cause of death, although this is fractionation on survival in rodents and beagle dogs.

Maisin and his colleagues have reported a seriesFile Size: 6MB.